Mexican White Trash Casserole made with Doritos, seasoned meat, Rotel tomatoes, and creamy cheese sauce. An easy baked dinner recipe packed with flavor and perfect for busy nights.

Why You’ll Love This Mexican White Trash Casserole

Some recipes are refined and delicate. This is not one of them. Mexican White Trash Casserole is bold, unapologetically cheesy, and incredibly satisfying. Crunchy nacho chips meet creamy sauce, seasoned meat, and melted cheese in a layered bake that feels indulgent yet comforting. It is the kind of meal you bring to potlucks, serve on game night, or prepare when you want something fun, filling, and guaranteed to disappear fast.

Preparation Time

Prep Time: 15 minutes

Bake Time: 20–25 minutes

Total Time: Approximately 40 minutes

Servings: 6–8 portions

Kitchen Tools You’ll Need

9×13-inch baking dish
Large mixing bowl
Wooden spoon or spatula
Measuring cups
Oven

Ingredients

1 bag Nacho Doritos, crushed
2 cups cooked chicken or seasoned ground beef
2 cups grated cheese (cheddar or Mexican blend)
1 can (10.75 oz) cream of chicken soup
1 can Rotel tomatoes, undrained
1/2 cup sour cream
1/2 cup milk
1/2 packet taco seasoning (adjust to taste)

Step-by-Step Instructions

Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish.
In a large mixing bowl, combine the cream of chicken soup, Rotel tomatoes (with juice), sour cream, milk, and taco seasoning. Stir until smooth.
Fold in the cooked chicken or seasoned ground beef and mix well.
Spread half of the crushed Doritos evenly across the bottom of the baking dish.
Pour the meat and sauce mixture over the chips, spreading evenly.
Sprinkle 1 1/2 cups of grated cheese over the top.
Add the remaining crushed Doritos and finish with the rest of the cheese.
Bake uncovered for 20–25 minutes, or until bubbly and the cheese is fully melted.
Let the casserole rest for 5–10 minutes before serving to help it set.

Tips for the Best Texture and Flavor

For extra crunch, reserve some Doritos and sprinkle them on during the last 5 minutes of baking. Use freshly grated cheese for smoother melting and better flavor. If the mixture feels too thick before baking, add a splash of milk to loosen it slightly. Allowing the casserole to rest after baking helps it slice more cleanly.

Easy Variations and Additions

Add black beans or corn for additional texture and heartiness. Stir diced jalapeños into the mixture for extra heat. Swap cream of chicken for cream of mushroom for a deeper savory note. Top with fresh cilantro, diced tomatoes, or sliced green onions before serving for brightness.

Storage and Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the oven at 325°F until warmed through for best texture. Microwave reheating works as well, though the chips will soften. Freezing is possible, but the chip texture will lose some crispness.

Approximate Nutrition Per Serving

Calories: 480–550
Protein: 28g
Carbohydrates: 35g
Fat: 28g
Fiber: 3g
Sodium: Varies based on seasoning and chips used

Frequently Asked Questions

Can I prepare this casserole ahead of time?

Yes. Assemble it up to 24 hours in advance and refrigerate. Bake just before serving.

Can I use rotisserie chicken?

Absolutely. Rotisserie chicken saves time and adds great flavor.

How do I make it less spicy?

Use mild Rotel tomatoes and reduce the taco seasoning amount.

Can I double the recipe?

Yes, simply use two baking dishes or a larger casserole pan and adjust baking time slightly.

Final Tip

This casserole is meant to be fun, flavorful, and a little indulgent. Do not overthink it. Layer generously, bake until bubbling, and serve it hot while the cheese stretches and the aroma fills the kitchen.